With its aggressively invasive vine system, creeping Charlie can be an extreme nuisance for homeowners, but you can remove it by safely using herbicides.

Getting rid of severe infiltrations of creeping Charlie may require pulling out the poison, so select a broadleaf herbicide with the active ingredients salt of dicamba or triclopyr.

Dicamba represses the weed's growth, but it may not be as effective if the roots of the weed are entangled with the fibrous roots

of turf grass.

Dicamba vaporizes and kills nearby plants even when applied directly to creeping Charlie, so avoid using it near vegetables, fruits, or flowers, and wear gloves, mask, and goggles.

Meanwhile, triclopyr kills creeping Charlie from the root up. It's a powerful toxin with health risks and should not be used to liberally treat expansive areas of weeds.

Doing so can lead to triclopyr leeching into aquifers and waterways, potentially contaminating drinking water and harming wildlife.

Don't treat creeping Charlie with chemicals if rain is forecasted within 24 hours of spraying and pick a day with little or no wind so the toxins don't transfer to other plants.

Ideally, you should plan to get rid of creeping Charlie after the first frost and use its poisoned, dead roots as compost.